Can You Take CBD and Xanax?

Xanax is the most popular prescribed drug for anxiety. On the other hand, CBD is also an anxiety reliever, leaving many wondering, can you take CBD and Xanax together? Whether you can take the two together depends on your overall health, dosage, and the type of CBD you are using. While it could be safe to mix CBD and Xanax, CBD often interacts with some drugs and causes adverse side effects. Therefore, you need to know whether the two can work together without risking your health.

Xanax is a prescription for anxiety and panic disorders and is part of the class of benzodiazepines. Also known as alprazolam, they come in tablets, and when you ingest them, they are released into the bloodstream to provide you with immediate calming effects. Professionals prescribe the drug for short-term use, but some people use it longer and sometimes form an addiction to the drug.

CBD is a natural compound that offers various health benefits, such as relieving anxiety. Its effectiveness results from its interaction with the endocannabinoid system. CBD comprises natural ingredients, making it safe and does not pose any adverse side effects. Regardless, you should seek professional advice before mixing the two.

How Does CBD Interact With Xanax?

CBDCBD inhibits the primary enzyme, P450, known to break down drugs, including benzodiazepines. In some instances, CBD binds with the enzymes, thus affecting how the drug is metabolized in your body. Consequently, CBD delays Xanax breakdown, making it stay in the bloodstream for longer hours than it should.

The interference of CBD results in increased levels of Xanax in your system, which could have adverse side effects on your overall health. The main side effects include drowsiness, increased risk of addiction, and disorientation. These side effects get worse when you add alcohol to the two. Also, if you should take CBD and Xanax together, get an opinion from a qualified physician.

Can CBD Replace Xanax?

CBD interferes with how Xanax works. To avoid the side effects of the combination, you can opt to use one instead of the other. You may want to replace Xanax with CBD because Xanax is a powerful anti-anxiety medication with various side effects. On the other hand, CBD is a natural compound that causes mild and short-term side effects when treating anxiety and other health conditions.

CBD interacts with your CB1 and CB2 receptors to restore the endocannabinoid system (ECS) balance. As a result, CBD effectively relieves anxiety with minimal interference to your well-being, making it safer than Xanax or any other benzodiazepines.

Even with a prescription, Xanax can cause addiction, and when you stop its usage can cause withdrawal, which could affect various body systems. Suddenly stopping can increase heart rate, blood pressure, respiration, and temperature. Moreover, you can experience seizures that could put you in a coma or cause death.

Some common symptoms of Xanax withdrawal include:

  • Suicidal thoughts
  • Depression
  • Anxiety
  • Short-term memory loss
  • Panic
  • Lack of emotional control

Common physical signs include:

  • Headache
  • Loss of appetite
  • Insomnia
  • Blurred vision
  • Heart palpitations
  • Hypertension

Combining these two medications requires a professional’s guidance who can suggest a dosage with minimal side effects.

Necessary Precautions When Taking Xanax

Alprazolam is a highly potent medication that requires caution when administering it. Consider the following factors while taking Xanax:

  • Pregnancy

Taking Xanax while pregnant could negatively affect the pregnancy. Therefore, consult your physician if you want to use the medicine while pregnant or plan to become pregnant.

  • Cessation


If you are on Xanax and want to stop using it, you must seek a physician’s advice beforehand. Abruptly stopping could result in undesirable outcomes like seizures. 

  • Dosage Adjustment

Always stick to the prescribed dosage, and any change should be with a doctor’s consent, even if you feel like you need a change. Xanax, even with a dosage, could cause dependence. Therefore, increasing the dosage could result in addiction, and stopping its usage will be hard.

  • Contaminant Medication

While using Xanax, you shouldn’t take other prescribed or over-the-counter medication.

Advantages and Disadvantages of CBD and Xanax

Both CBD and Xanax have their pros and cons for treating anxiety. They include:

Pros of CBD

  • Non-addictive
  • Reduces inflammation
  • Improves pain
  • Soothes pain
  • All-natural
  • Boosts immune system

Cons of CBD

  • Dry mouth
  • Drowsiness
  • Low blood pressure
  • Diarrhea

Pros of Xanax

  • Works fast
  • Strong calming effects
  • Treats anxiety

Cons of Xanax

  • Addictive
  • Difficulty focusing
  • Tolerance forming
  • Drowsiness and dizziness
  • Severe withdrawal
  • Memory impairment
  • Slurred speech

How to Stop Using Xanax

It is essential to know what to do because it will reduce your risk of having withdrawal symptoms when you stop taking the drugs. When you stop taking alprazolam suddenly, withdrawal symptoms can be severe and include feelings of anxiety and agitation, confusion, insomnia, muscle cramps, seizures, or heart palpitations.

Additionally, suppose you have been taking high doses of Xanax or using them regularly for an extended period. Your body may take longer than normal to adjust to being drug-free again. In this case, it’s best to slowly taper off over a few days or weeks rather than stop abruptly. The exact amount of time needed will vary from one person to another based on the time they have used the drugs.


CBD and alprazolam are excellent remedies to stress and panic disorders. However, the interaction causes adverse side effects since CBD inhibits the enzymes responsible for alprazolam rehabilitation. Can you use CBD and Xanax? No. We don’t recommend mixing the two. However, if you must use the combination, ensure that you do so under a doctor’s supervision.

CBD has several health benefits, while Xanax poses many adverse side effects. If you are already using alprazolam and wish to replace it with CBD, we recommend that you consult your doctor, who will guide you on the withdrawal process. Mixing CBD with Xanax is a bad idea since it could lead to drug interactions. If you intend to mix them, you need to space the doses to allow the metabolization of each drug before using the other.

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